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Paper Information

Journal:   INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY   SUMMER 2011 , Volume 5 , Number SUPPLEMENT 1; Page(s) 73 To 73.
 
Paper: 

FEMALE INFERTILITY: DISCONTINUATION OF RLH TWO DAYS BEFORE HCG MAY INCREASE THE NUMBER OF OOCYTES RETRIEVED IN IVF

 
 
Author(s):  SPENCER J.B.*, BROWNE A.S., COPLAND S.D., SESSION D.R.
 
* EMORY UNIVERSITY, ATLANTA, GA, USA
 
Abstract: 

Background: Administration of recombinant luteinizing hormone (rLH) in controlled ovarian hyperstimulation may benefit a subpopulation of patients. However, late follicular phase administration of high doses of rLH may also reduce the size of the follicular cohort and promote monofollicular development.
Materials and Methods: To determine if rLH in late follicular development had a negative impact on follicular growth and oocyte yield, IVF patients in our practice who received rFSH and rLH for the entire stimulation were retrospectively compared with those that had the rLH discontinued at least two days prior to hCG trigger.
Results: The two groups had similar baseline characteristics before stimulation with respect to age, FSH level and antral follicle count. However, the group which had the rLH discontinued at least two days prior to their hCG shot, had a significantly higher number of oocytes retrieved, including a higher number of MII oocytes and number of 2PN embryos.
Conclusion: When using rLH for controlled ovarian hyperstimulation, administering it from the start of stimulation and stopping it in the late follicular phase, at least two days prior to hCG trigger, may increase oocyte and embryo yield.

 
Keyword(s): RECOMBINANT LUTEINIZING HORMONE, RLH, LH, OVARIAN STIMULATION, IVF, POOR RESPONDERS
 
 
References: 
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Click to Cite.
APA: Copy

SPENCER, J., & BROWNE, A., & COPLAND, S., & SESSION, D. (2011). FEMALE INFERTILITY: DISCONTINUATION OF RLH TWO DAYS BEFORE HCG MAY INCREASE THE NUMBER OF OOCYTES RETRIEVED IN IVF. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 5(SUPPLEMENT 1), 73-73. https://www.sid.ir/en/journal/ViewPaper.aspx?id=273107



Vancouver: Copy

SPENCER J.B., BROWNE A.S., COPLAND S.D., SESSION D.R.. FEMALE INFERTILITY: DISCONTINUATION OF RLH TWO DAYS BEFORE HCG MAY INCREASE THE NUMBER OF OOCYTES RETRIEVED IN IVF. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY. 2011 [cited 2021May13];5(SUPPLEMENT 1):73-73. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273107



IEEE: Copy

SPENCER, J., BROWNE, A., COPLAND, S., SESSION, D., 2011. FEMALE INFERTILITY: DISCONTINUATION OF RLH TWO DAYS BEFORE HCG MAY INCREASE THE NUMBER OF OOCYTES RETRIEVED IN IVF. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, [online] 5(SUPPLEMENT 1), pp.73-73. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273107.



 
 
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