Paper Information

Journal:   ADVANCES IN COGNITIVE SCIENCE   FALL 2007 , Volume 9 , Number 3 (35); Page(s) 20 To 25.
 
Paper: 

BRAIN IMAGING CHARACTERISTICS IN TRANSSEXUAL AND NORMAL INDIVIDUALS

 
 
Author(s):  OHADI BEHNAM, MOHAMMADI MOHAMMAD REZA, RAHIMIAN ELHAM, RAISI FIROOZEH, SABERI MEHDI, ARBABI MOHAMMAD, MEISAMI ALI PASHA, NOROOZIAN MARYAM
 
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Abstract: 

Objective: The aim of this study was to compare the brain imaging characteristic of transsexuals with normal individuals.
Method: In this descriptive analytical study 30 person were selected by sequentional sampling in two control and case groups that had the inclusion criteria and did not have the exclusion criteria from patients admitted to Rouzbeh Hospital and forensic medical organization. Demographic information such as height, weight, head circumference and BMI were obtianed and brain MRI performed by 3D FSE method. Collected data were analyzed by Analyze volumetric software (Mayo Foundation, Rochester). Red nucleus, CSF, intradural and paranchima volume and Corpus collasum area were analyzed statisticaly using T-test Pearson correlation coefficient tests.
Results: Red nucleus volume difference between case and control groups were significant. Difference of red nucleus, paranchima and IDV volume between male and females were significant too. In addition there was no significant difference in red nucleus volume between male patients and normal females but the difference between female patients and normal males was significant.
Conclusion: in this study difference in brain anatomical structure between transsexuals and normal individuals observed. It seems that maybe sometime in the process of development and CSF differentiation in prenatal period and intrauterine life brain anatomical structure changed and does not follow the normal pathway consistent with ones gender.

 
Keyword(s): GENDER IDENTITY DISORDER, TRANSSEXUALISM, BRAIN IMAGING, MRI VOLUMETRY
 
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