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Paper Information

Journal:   INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY   SUMMER 2011 , Volume 5 , Number SUPPLEMENT 1; Page(s) 56 To 56.
 
Paper: 

EPIDEMIOLOGY AND ETHICS: THE EFFECTS OF CADMIUM AS A HEAVY METAL ON FERTILITY AND OFFSPRING’S GROWTHS OF MALE AND FEMALE MICE

 
 
Author(s):  ALAEE S.*, MONSEFI M., ROHANI L.
 
* DEPARTMENT OF BIOLOGY AND ANATOMY, SCHOOL OF MEDICINE, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, TEHRAN, IRAN
 
Abstract: 

Background: Cadmium a common environmental pollutant and a major constituent of tobacco smoke, are dangerous because it can bioaccumulate in a biological organism over time and has been identified as a detrimental element for mammalian reproductive system. Most of cadmium which enters the body comes from terrestrial foods or meat from animals which have ingested plants grown in soil containing high levels of cadmium. Our previous study demonstrated that cadmium causes to decrease weight of testis, serum testosterone, sperm count and motility. Also testicular tissue showed severe necrosis in almost all of the seminiferous tubules. In this study we investigated the effects of cadmium in a concentration similar to that found in Maharloo Lake (Shiraz, Iran) on fertility of male and female mice and their offspring’s growth.
Materials and Methods: Balb/c male and female mice divided to low dose (I) and high dose (II) administered group that received 23 and 50 mg/kg of cadmium chloride respectively in 0.5 ml distilled water for 45 days. The control group (C) received only equal volumes of distilled water under similar conditions. After last day of cadmium chloride administration male and female animals from each group were mated in following manner: male (C) and female (C), male (C) and female (I), male (C) and female (II), male (I) and female (I), male (II) and female (II), male (I) and female (C), male (II) and female (C). After the termination of pregnancy, the number of offsprings was counted then their crown rump length (CRL) and weights were measured in1st, 5th, 10th, 15th and 20th days after birth.
Results: Our results showed that there was no successful mating between male (II) and females in (C) and (II). Number of offsprings from mating of male (I) and female (C) and (I) were lower than mating of Male (C) and female (C). Weigths and CRL of offsprings from mating of male (C) and female (I) were similar to offsprings from mating male (C) and female (C) but Weigths and CRL of offsprings from mating of male (C) and female (II) were significantly lower in 1rd, 5th and 10th day in compared to offsprings of male (C) and female (C).
Conclusion: We concluded that the level of cadmium in underground and pool water around Shiraz is dangerous for the mammalian reproductive system in that area.

 
Keyword(s): CADMIUM, FERTILITY, REPRODUCTIVE SYSTEM
 
 
References: 
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Click to Cite.
APA: Copy

ALAEE, S., & MONSEFI, M., & ROHANI, L. (2011). EPIDEMIOLOGY AND ETHICS: THE EFFECTS OF CADMIUM AS A HEAVY METAL ON FERTILITY AND OFFSPRING’S GROWTHS OF MALE AND FEMALE MICE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 5(SUPPLEMENT 1), 56-56. https://www.sid.ir/en/journal/ViewPaper.aspx?id=272668



Vancouver: Copy

ALAEE S., MONSEFI M., ROHANI L.. EPIDEMIOLOGY AND ETHICS: THE EFFECTS OF CADMIUM AS A HEAVY METAL ON FERTILITY AND OFFSPRING’S GROWTHS OF MALE AND FEMALE MICE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY. 2011 [cited 2021May11];5(SUPPLEMENT 1):56-56. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=272668



IEEE: Copy

ALAEE, S., MONSEFI, M., ROHANI, L., 2011. EPIDEMIOLOGY AND ETHICS: THE EFFECTS OF CADMIUM AS A HEAVY METAL ON FERTILITY AND OFFSPRING’S GROWTHS OF MALE AND FEMALE MICE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, [online] 5(SUPPLEMENT 1), pp.56-56. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=272668.



 
 
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