Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES   MARCH-APRIL 2012 , Volume 15 , Number 2; Page(s) 787 To 791.
 
Paper: 

INHIBITORY ACTIVITY OF ELEVEN ARTEMISIA SPECIES FROM IRAN AGAINST LEISHMANIA MAJOR PARASITES

 
 
Author(s):  EMAMI SEYED AHMAD, ZAMANAI TAGHIZADEH RABE SHAHRZAD, AHI ALI, MAHMOUDI MAHMOUD*
 
* IMMUNOLOGY RESEARCH CENTRE, BU ALI RESEARCH INSTITUTE, SCHOOL OF MEDICINE, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, MASHHAD, IRAN
 
Abstract: 

Objective(s): Annual incidence of cutaneous leishmaniasis is increasingly growing and development of the alternative drugs against it is a major concern. Artemisia genus is a traditional medicinal plant in Iran. The aim of this study was to examine the leishmanicidal activity of various Iranian Artemisia species extracts.
Materials and Methods: Different extracts were gathered from eleven Iranian Artemisia species. Their leishmanicidal activIties against the growth of Leishmania major (L. major) promastigotes were examined as the half maximal inhibitory concentration (lCso) using MTT assay.
Results: Obtained results showed that ethanol extracts especially those taken fromA. ciniformis, A. santolina and A. kulbadicahave the strongest effects.
Conclusion: Looking for the effective leishmanicidal agents from natural resources in Iran, we found that the ethanol extract of collected Artemisia species had significant effect on in vitro leishmanicidal activity and may be suitable candidates in the treatment of leishmaniasis.

 
Keyword(s): ARTEMISIA, LEISHMANICIDAL ACTIVITY, LEISHMANIA MAJOR, MTT ASSAY, PROMASTIGOTE
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 91
 
Latest on Blog
Enter SID Blog