Paper Information

Journal:   WORLD JOURNAL OF PLASTIC SURGERY   JULY 2012 , Volume 1 , Number 2; Page(s) 83 To 90.
 
Paper: 

THE SYNERGISTIC EFFECT OF BLEOMYCIN, TRIAMCINOLONE AND EPINEPHRINE IN TREATMENT OF HEMANGIOMA AND ARTERIOVENOUS MALFORMATIONS

 
 
Author(s):  MASIHA HAMID, NIKPOUR HEYDAR ALI, HASANI MOHAMMAD ESMAEIL, EMAMI ABOLHASAN, JAFARI SEYED MEHRYAR, MANAFI ALI*
 
* DEPARTMENT OF PLASTIC SURGERY, TEHRAN UNIVERSITY OF MEDICAL SCIENCES, SAMSUNG BLDG, 3RD FLOOR, SUITE 305, VANAK SQUARE, TEHRAN, IRAN
 
Abstract: 

BACKGROUND: Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations.
METHODS: In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients.
RESULTS: Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor.
CONCLUSION: It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations.

 
Keyword(s): BLEOMYCIN, TRIAMCINOLONE, EPINEPHRINE, HEMANGIOMA, ARTERIOVENOUS MALFORMATION
 
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