Paper Information

Journal:   DERMATOLOGY AND COSMETIC   SUMMER 2012 , Volume 3 , Number 2; Page(s) 83 To 91.
 
Paper: 

EFFECT OF NARROW BAND UVB ON NORMAL FLORA OF LESIONAL AND NORMAL SKIN IN PSORIATIC PATIENTS

 
Author(s):  FARSHCHIAN MAHMOOD, SOLTANIE ELAHEH*, MOOSAVI LEILA, MAHJOUB HOSSEIN, ZAMANIAN ABBAS, NAZERIAN HALEH
 
* DERMATOLOGY WARD, FARSHCHIAN HOSPITAL, HAMEDAN, IRAN
 
Abstract: 

Background and Aim: Psoriasis is a chronic inflammatory dermatosis that affects 0.6% to 4.8% of the general population. Our aim was to compare the effect of narrow band UVB (NBUVB) on normal flora of cutaneous plaques and normal skin in psoriatic patients.
Methods: Twenty psoriatic patients without any contraindication of phototherapy were enrolled in this study. Samples from psoriatic lesions and adjacent normal skin, before and after phototherapy with NB-UVB were taken. Patients were treated with NB-UVB three times weekly until complete remission. Finally, quantity of normal cutaneous flora on normal and involved skin, before and after treatment was compared.
Results: The mean±SD of the NB-UVB sessions and the mean cumulative dose were 26.35±4.95 and 2.05±0.57 J/cm2, respectively. The number of Staphylococcus epidermidis, S. aureusand diphtheroids on psoriatic plaques reduced after phototherapy.
Conclusion: The quantity of normal cutaneous flora on normal skin is less than psoriatic plaques, and it reduced on normal and involved skin after phototherapy.

 
Keyword(s): PSORIASIS, NB-UVB, NORMAL CUTANEOUS FLORA, STAPHYLOCOCCUS AUREUS, S. EPIDERMIDIS
 
References: 
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