Paper Information

Journal:   JOURNAL OF MEDICINAL PLANTS   December 2003 , Volume 2 , Number 8; Page(s) 35 To 40.
 
Paper: 

EFFECT OF ESSENTIAL OILS OF ARTEMISIA AUCHERI BOISS. ZATARIA MULTIFLORA BOISS AND MYRTUS COMMUNIS L. ON TRICHOMONAS VAGINALIS

 
 
Author(s):  AZADBAKHT M.*, ZIAI H., SHAABAN KHANI B.
 
* Sari,Iran
 
Abstract: 
Considering the high prevalence of Tricomonas vaginalis (TV) in women and the known side effects of metronidazol and given importance to herbal drug therapy in order to reduce side effects in the recent decades, this study with the effect of essential oils of Artemisia aucheri Boiss., Zataria multiflora Boiss. And Myrtus communis L. in TV infection was done invitro condition. This study has been carried out as double blind in test and control groups. The essential oils prepared by hydrodistilation. The parasite was isolated from vagina and determined directly. Samples were callected from vaginal discharge discharge identification was done through direct smear preasite was added to the 5 test tubes containing dorsse medium, metronidazole Dimethyl sulfoxaide (DMSO) and the essenrial oils with concentrations of (0.1, 0.01, 0.001 - 0.004, 0.0002, 0.0001) in order to determine the effect of these concentration within 72 hour. Finding if this study showed that , Trichomonas could be alived in Dorsse medium for 72 hours. In presence of metrinidazole for one hour and in Dorsse medium for 6 hours. The results revealed that, essential oil of Artemisia at concentrations of 0.1, 0.01, 0.001 are effective at the beginning of the inoculation and at concentrations of 0.0004 and 0.0001 after 1 and 2 hours respectively. Essential oil of Zataria at concentration of 0.1, 0.01, 0.001and 0.0004 are effective at the beginning of the inoculation and at concentrations of 0.0002 and 0.0001 after 1 hour. Essential of Myrtus at concentration of 0.1, 0.01 , 0.001 and 0.0004 are effective at the beginning of the inoculation and at concentrations of 0.0002 and 0.0001 after 2 and 4 hours respectively. Considering the significant effect of essential oils of Artemisia, Zataria and Myrtus on trichomona in in vitro condition it is recommended that, the therapeutic effects the substance from this plant be studied in in vitro condition and in case of having positive effect to be used as a drug.
 
Keyword(s): ARTEMISIA AUCHERI BOISS, ZATARIA MULTIFLORA BOISS., MYRTUS COMMUNIS L., TRICOMONAS VAGINALIS, MEDICINAL PLANT, ESSENTIAL OIL.
 
References: 
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