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Paper Information

Journal:   JOURNAL OF MEDICINAL PLANTS   March 2004 , Volume 3 , Number 9; Page(s) 35 To 42.
 
Paper: 

FORMULATION OF HERBAL ANTIPERSPIRANT FROM PAROTIA PERSICA (DC.) C.A.MEY. (HAMAMELIS PERSICA) AND PRELIMINARY CLINICAL STUDY

 
 
Author(s):  AZADBAKHT M.*, AKBARI J., PASANDI S.
 
* Mazandaran University of medical Sciences, Faculty of Pharmacy
 
Abstract: 
Parotia persica syn. Hamamelis persica (Hamamelidaceae) is indigenous in north province of Iran. Other species, Hamamelis virginiana, is grown in north of America and has a little distribution in the Europe. Plentiful investigation was performed on the Hamamelis virginiana and species but there is no study about Hamamelis persica and this study is the first report regarding the clinical and phytochemical study of the plant.
Hamamelis persica leaves were collected in May, August and October of 1999 from Mazandaran. Extraction was accomplished from the leaves through percolation by ethanol 70. Tannins were measured by spectrophotometric method. For the clinical study as antiperspirant, a roll-on preparation was formulated on the extract by using of glycerol, propylene glycol, water, carbapol 934p, antioxidant: The formulation was prepared in suitable viscosity. The product stability was evaluated during 5 months. Then the product and placebo were given to volunteers. The clinical; study was performed in a blind study by questionnaire. Results showed that the leaves contain mainly pyrogallol group tannins (6.11%). The product had suitable stability in clinical study. Sweating was reduced in 85precent of the volunteers that used product as roll-on in armpit.
 
Keyword(s): ANTIPERSPIRANT, HAMAMELIS PERSICA, PYROGALLOL, TANNIN, ROLL-ON
 
References: 
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