ASSESSMENT OF THE EFFECTS OF SOY ISOFLAVONES ON LIPID PROFILE AND BLOOD SUGAR LEVELS IN HYPERCHOLESTEROLEMIC RABBITS

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AMANI R.; BAGHDADCHI J.; ZAND MOGHADAM A.

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Journal: Jundishapur Scientific Medical Journal Year:2002 | Volume:- | Issue:34 Page(s): 25-32

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Title

ASSESSMENT OF THE EFFECTS OF SOY ISOFLAVONES ON LIPID PROFILE AND BLOOD SUGAR LEVELS IN HYPERCHOLESTEROLEMIC RABBITS

Author(s)

AMANI R. | BAGHDADCHI J. | ZAND MOGHADAM A. | Issue Writer Certificate

Keywords

SOY ISOFLAVONESQ4

LIPIDQ3

SUGARQ3

RABBITQ3

Abstract

The main objective of this research was to determine the effects of SOY ISOFLAVONES on serum LIPIDs, lipoproteins and fasting blood SUGAR levels in hypercholesterolemic RABBITs. Twenty four male New Zealand RABBITs received basic pellete diet for two weeks and then were placed on hypercholesterolemic diets (pelletes plus 1% cholesterol) for three weeks. After elevation of total and LDL-cholesterol (about ten folds), groups 1-3 received 100g soy protein containing 200gr (ISO++), 100mg (ISO+) and soy protein diet without isoflavones (ISO-), for six weeks, respectively, and group 4 kept on hypercholesterolemic diet (CHO).Results showed no change in total and LDL-cholesterol levels with ISO++ diet, but two folds increases with ISO+ and ISO- in comparison with baseline and CHO diets (P<0.000). HDL-cholesterol significantly increased after ingestion of CHO diet and remained elevated (almost three folds) by the soy diets. Triglycerides and VLDL-cholesterol increased by all soy diets but only in ISO+ and ISO- diets were significantly higher than baseline (P<0.05).Fasting blood SUGAR levels were not changed by the soy diets. These results suggest that SOY ISOFLAVONES have ameliorated the LIPID profile but have not changed blood SUGAR levels so can exert clinical improvement in hyperlipidemias specially when cholesterol intake is simultaneously decreases.

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APA: Copy

AMANI, R., BAGHDADCHI, J., & ZAND MOGHADAM, A.. (2002). ASSESSMENT OF THE EFFECTS OF SOY ISOFLAVONES ON LIPID PROFILE AND BLOOD SUGAR LEVELS IN HYPERCHOLESTEROLEMIC RABBITS. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, -(34), 25-32. SID. https://sid.ir/paper/395090/en

Vancouver: Copy

AMANI R., BAGHDADCHI J., ZAND MOGHADAM A.. ASSESSMENT OF THE EFFECTS OF SOY ISOFLAVONES ON LIPID PROFILE AND BLOOD SUGAR LEVELS IN HYPERCHOLESTEROLEMIC RABBITS. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2002;-(34):25-32. Available from: https://sid.ir/paper/395090/en

IEEE: Copy

R. AMANI, J. BAGHDADCHI, and A. ZAND MOGHADAM, “ASSESSMENT OF THE EFFECTS OF SOY ISOFLAVONES ON LIPID PROFILE AND BLOOD SUGAR LEVELS IN HYPERCHOLESTEROLEMIC RABBITS,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. -, no. 34, pp. 25–32, 2002, [Online]. Available: https://sid.ir/paper/395090/en

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