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Paper Information

Journal:   SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES JOURNAL   APRIL-MAY 2011 , Volume 13 , Number 1; Page(s) 21 To 26.
 
Paper: 

EFFECTS OF SESAMUM INDICUM L. ON FIBRINOGEN AND FACTOR 7 IN HYPERCHOLESTEROLEMIC RABBITS

 
 
Author(s):  ASGHARY S., SHIRZAD H., HEIDARIAN E., MIRHOSSEINI M., ANSARY R., SHAHINFARD N., ASHRAFI K., HEYDARI Z., RAFIEIAN M.*
 
* MEDICAL PLANTS RESEARCH CENTER, RAHMATIEH, SHAHREKORD UNIV. OF MED. SCI. SHAHREKORD, IRAN
 
Abstract: 

Background and aim: Enhancement of blood factor 7 or fibrinogen is considered as cardiovascular risk factors. This study was, therefore, aimed to evaluate the effects of Sesamum indicum seed and oil on fibrinogen and factor 7 in hypercholesterolemic rabbits.
Methods: In an experimental study, 32 NewZealand rabbits were randomly designated into 4 groups of 8 and were fed for 60 days as following: normal diet, hypercholestrol (1%) diet, hypercholestrol (1%) diet+10% sesame seed, hypercholestrol (1%) diet+5% sesame oil. At the beginning and 60 days after the start of the study, the blood fibrinogen and factor 7 were measured and compared in different groups.
Results: There was no difference for fibrinogen and factor 7 in different groups at the start of the study, however, the blood fibrinogen and factor 7 were increased in hypercholesterolemic group compared to normal diet group (P<0.05). The amounts of blood fibrinogen and factor 7 were decreased in hypercholesterol+sesame seed and in hypercholesterol+sesame oil groups compared to hypercholesterol diet group (P<0.05).
Conclusion: Sesame seed and oil may have beneficial effects on cardiac function by decreasing blood fibrinogen and factor 7 as cardiovascular risk factors.

 
Keyword(s): FACTOR 7, FIBRINOGEN, HYPERCHOLESTEROLEMIA, SESAME
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

ASGHARY, S., & SHIRZAD, H., & HEIDARIAN, E., & MIRHOSSEINI, M., & ANSARY, R., & SHAHINFARD, N., & ASHRAFI, K., & HEYDARI, Z., & RAFIEIAN, M. (2011). EFFECTS OF SESAMUM INDICUM L. ON FIBRINOGEN AND FACTOR 7 IN HYPERCHOLESTEROLEMIC RABBITS. SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 13(1), 21-26. https://www.sid.ir/en/journal/ViewPaper.aspx?id=193907



Vancouver: Copy

ASGHARY S., SHIRZAD H., HEIDARIAN E., MIRHOSSEINI M., ANSARY R., SHAHINFARD N., ASHRAFI K., HEYDARI Z., RAFIEIAN M.. EFFECTS OF SESAMUM INDICUM L. ON FIBRINOGEN AND FACTOR 7 IN HYPERCHOLESTEROLEMIC RABBITS. SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES JOURNAL. 2011 [cited 2021July30];13(1):21-26. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=193907



IEEE: Copy

ASGHARY, S., SHIRZAD, H., HEIDARIAN, E., MIRHOSSEINI, M., ANSARY, R., SHAHINFARD, N., ASHRAFI, K., HEYDARI, Z., RAFIEIAN, M., 2011. EFFECTS OF SESAMUM INDICUM L. ON FIBRINOGEN AND FACTOR 7 IN HYPERCHOLESTEROLEMIC RABBITS. SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES JOURNAL, [online] 13(1), pp.21-26. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=193907.



 
 
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