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Paper Information

Journal:   BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN)   WINTER 2009 , Volume 3 , Number 4; Page(s) 1 To 7.
 
Paper: 

EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS

 
 
Author(s):  EIDI A.*, MINAIEE TEHRANI D., HATAMI M.
 
* DEPARTMENT OF BIOLOGY, SCIENCE AND RESEARCH BRANCH, ISLAMIC AZAD UNIVERSITY, TEHRAN, IRAN
 
Abstract: 

Olive (Olea europeae L.) is a tree that has been used as a hepatoprotective and antioxidant agent in traditional medicine. In present study, the protective effects of ethanolic extract of olive leaves in rats were evaluated. Wistar rats were orally treated with olive leaves extract (10, 100, 200 and 400 mg/kg) along with administration of CCl4 (50% CCl4/sunflower oil; 1ml/kg) for 28 days. The results showed that the treatment of olive leaves extract significantly lowered the CCl4-induced serum levels of hepatic enzyme markers AST (aspartate amino transferase) and ALT (alanine amino transferase). Therefore, the results of the study suggest that the extract could protect liver against the CCl4-induced oxidative damage in rats, and this hepatoprotective effect might be attributed to its modulation on detoxification enzymes, its antioxidant and free radical scavenger effects.

 
Keyword(s): OLIVE, DETOXIFICATION, LIVER, RAT, AST, ALT
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

EIDI, A., & MINAIEE TEHRANI, D., & HATAMI, M. (2009). EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS. BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN), 3(4), 1-7. https://www.sid.ir/en/journal/ViewPaper.aspx?id=192918



Vancouver: Copy

EIDI A., MINAIEE TEHRANI D., HATAMI M.. EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS. BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN). 2009 [cited 2021July30];3(4):1-7. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=192918



IEEE: Copy

EIDI, A., MINAIEE TEHRANI, D., HATAMI, M., 2009. EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS. BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN), [online] 3(4), pp.1-7. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=192918.



 
 
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