Paper Information

Journal:   HEPATITIS MONTHLY   MARCH 2011 , Volume 11 , Number 3 (32); Page(s) 173 To 177.
 
Paper: 

MILK THISTLE FOR TREATMENT OF NONALCOHOLIC FATTY LIVER DISEASE

 
 
Author(s):  ABENAVOLI L.*, AVIELLO G., CAPASSO R., MILIC N., CAPASSO F.
 
* DEPARTMENT OF EXPERIMENTAL AND CLINICAL MEDICINE, UNIVERSITY OF MAGNA GRÆCIA, VIALE EUROPA, CATANZARO, ITALY
 
Abstract: 

Nonalcoholic fatty liver disease (NAFLD) is one the most common causes of chronic liver dis­orders in the Western world. These patients have much significant comorbidity. The thera­peutic approach to NAFLD is based on lifestyle intervention, but there is no consensus on the ideal pharmacological treatment. Silybum marianum, commonly known as milk thistle (MT), is one of the oldest and most extensively researched plants in the treatment of liver diseases. Many studies have demonstrated that the active components of MT silymarin have many hepatoprotective properties. In recent years, several preclinical and clinical reports have described the efficacy of silymarin as a treatment for NAFLD. The chief aim of this review is to discuss the newest and most promising applications of MT in the treatment of NAFLD….

 
Keyword(s): MILK THISTLE, SILYMARIN, NONALCOHOLIC FATTY LIVER DISEASE, FIBROSIS, INSULIN RESISTANCE
 
References: 
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