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Paper Information

Journal:   TANAFFOS   WINTER 2011 , Volume 10 , Number 1; Page(s) 8 To 11.
 
Paper: 

PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN

 
 
Author(s):  MORADI AHMADREZA, NADJI SEYED ALIREZA*, TABARSI PAYAM, HASHEMIAN SEYED MOHAMMADREZA, MARJANI MAJID, SIGAROODI AFSANEH, MANSOURI DAVOOD, MASJEDI MOHAMMADREZA, VELAYATI ALI AKBAR
 
* NRITLD, SHAHEED BAHONAR AVE, DARABAD, TEHRAN 19569, IRAN
 
Abstract: 
Background: Oseltamivir-resistant cases were reported during the 2009 pandemic influenza outbreak and therefore, widespread emergence of oseltamivir-resistant 2009 H1N1 virus is imaginable. Underlying medical conditions like immunosuppression increase the chance of oseltamivir resistance.
Materials and Methods: In a retrospective cross-sectional study, respiratory tract specimens of confirmed cases of 2009 H1N1 influenza referred to the Masih Daneshvari Hospital were analyzed for presence of H275Y mutation.
Results: From November 2009 through March 2010, oseltamivir- resistant 2009 H1N1 infection was observed and confirmed in 4 patients (including 2 immunocompromised patients) by performing H275Y mutation molecular testing.
Conclusion: Close monitoring of resistance to neuraminidase inhibitors is essential in tertiary care centers. The H275Y mutation (oseltamivir-resistant genotype) could appear in the absence or presence of selective drug pressure.
 
Keyword(s): PANDEMIC 2009 H1N1 VIRUS, H275Y MUTATION, OSELTAMIVIR-RESISTANCE
 
 
References: 
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Citations: 
 
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APA: Copy

MORADI, A., & NADJI, S., & TABARSI, P., & HASHEMIAN, S., & MARJANI, M., & SIGAROODI, A., & MANSOURI, D., & MASJEDI, M., & VELAYATI, A. (2011). PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN. TANAFFOS, 10(1), 8-11. https://www.sid.ir/en/journal/ViewPaper.aspx?id=191770



Vancouver: Copy

MORADI AHMADREZA, NADJI SEYED ALIREZA, TABARSI PAYAM, HASHEMIAN SEYED MOHAMMADREZA, MARJANI MAJID, SIGAROODI AFSANEH, MANSOURI DAVOOD, MASJEDI MOHAMMADREZA, VELAYATI ALI AKBAR. PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN. TANAFFOS. 2011 [cited 2021July28];10(1):8-11. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=191770



IEEE: Copy

MORADI, A., NADJI, S., TABARSI, P., HASHEMIAN, S., MARJANI, M., SIGAROODI, A., MANSOURI, D., MASJEDI, M., VELAYATI, A., 2011. PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN. TANAFFOS, [online] 10(1), pp.8-11. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=191770.



 
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