Paper Information

Journal:   IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)   WINTER 2011 , Volume 10 , Number 1; Page(s) 149 To 154.
 
Paper: 

COMPARISON OF VAGINAL MISOPROSTOL WITH FOLEY CATHETER FOR CERVICAL RIPENING AND INDUCTION OF LABOR

 
 
Author(s):  VAHID ROUDSARI FATEMEH, AYATI S.*, GHASEMI MARZIEH, HASANZADEH MOFRAD M., SHAKERI M.T., FARSHIDI F., SHAHABIAN M.
 
* WOMEN’S HEALTH RESEARCH CENTER, DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, GHAEM HOSPITAL, MASHHAD, IRAN
 
Abstract: 

At times, despite an unripe cervix, induction of labor may be needed. In these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. The aim of this study is the comparison of vaginal misoprostol with Foley catheter for cervical ripening and induction of labor. This randomized clinical trial was performed on 108 pregnant women who had referred to the teaching hospitals of Mashhad University of Medical Sciences during a time period of September 2007 to March 2008. These women were randomly divided into two groups: Misoprostol (including 49 patients) and Foley catheter (including 59 patients). For the first group, 25 microgram vaginal misoprostol was administered every 4 h up to maximum 6 doses. For the second group, Foley catheter 18 F, inflated with 50 cc of sterile water, was placed through the internal os of the cervix. Data was analyzed using SPSS software. p<0.05 was considered statistically significant. Two groups were similar in the view of demographic characteristics, cesarean indications, maternal and fetal outcomes and neonatal outcomes. Vaginal delivery was significantly higher in misoprostol group (89.9 vs. 62.7, p < 0.01). The mean of delivery time was significantly shorter in misoprostol group (11.08 ± 5.6 vs. 13.6 ± 16.0 h, p < 0.05). In the cases of pregnancy termination and unripe cervix, two methods of misoprostol and Foley catheter were considered suitable, but it seemed that misoprostol decreases the delivery time and was needed for the cesarean section.

 
Keyword(s): MISOPROSTOL, FOLEY CATHETER, CERVICAL RIPENING, INDUCTION OF LABOR
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 72
 
Latest on Blog
Enter SID Blog