Paper Information

Journal:   IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)   WINTER 2011 , Volume 10 , Number 1; Page(s) 1 To 2.
 
Paper: 

EDITORIAL: PET RADIOPHARMACEUTICALS

 
 
Author(s):  SHAHHOSSEINI S.*
 
* SCHOOL OF PHARMACY, SHAHEED BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

PET (Positron Emission Tomography) is a powerful imaging technique through which quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body can be realized. Positrons (b+) are positively charged beta particles. They are emitted when the atom is proton enriched. A positron has only a transient existence. After losing all of its kinetic energy, it interacts with an electron and is annihilated. Both the mass of positron and electron are converted to energy during annihilation and two 511 KeV photons are emitted at a 180° angle to each other. The PET is based on the coincidence detection of the two aforementioned photons. Coincidence detection is a powerful method enhancing sensitivity and dynamic-imaging capabilities of PET. PET camera systems contain a ring of detectors that encircles the patient. The data collected over many angles around the body axis of the patient is used to reconstruct the image of the activity distribution in slice or tomographic form.

 
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