Worldly life is naturally accompanied with some limitations and difficulties and some people, lacking enough awareness and patience, cannot meet them in a rational way. Some people, however, are of such a degree of awareness and patience that leads them to a rational way. They face the difficulties and limitations as some educational situations and, in addition, take their good opportunities and abilities into consideration more. Such a manner of life is the command of reason. This paper has centered on this active and hopeful manner of life as an agent against despair and depression.