Paper Information

Journal:   INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY   JANUARY-MARCH 2011 , Volume 4 , Number 4; Page(s) 168 To 171.
 
Paper: 

EVALUATION OF HOMOCYSTEINE LEVELS IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME

 
 
Author(s):  SALEHPOUR S.*, MANZOUR ALAJDAD A., NEYSANI SAMANI E., ABADI A.R.
 
* DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, INFERTILITY AND REPRODUCTIVE HEALTH RESEARCH CENTER (IRHRC), SHAHID BEHESHTI UNIVERSITY (MC.S), TEHRAN, IRAN
 
Abstract: 

Background: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls.
Materials and Methods: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed.
Results: The mean level of homocysteine was 16.25
± 11.94 mmol/L in patients with PCOS and 11.58 ± 3.82 mmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women.
Conclusion: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.

 
Keyword(s): POLYCYSTIC OVARY SYNDROME, HOMOCYSTEINE BLOOD, CARDIOVASCULAR DISEASE
 
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