Paper Information

Journal:   JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD)   WINTER 2011 , Volume 14 , Number 4 (48); Page(s) 305 To 315.
 
Paper: 

ANGIOGENESIS AND TUMOR

 
 
Author(s):  MANSOURI KAMRAN*, MOSTAFAEI ALI, MOHAMMADI MOTLAGH H.R.
 
* 
 
Abstract: 

Angiogenesis, the process of new blood vessel formation from existing ones, plays an important role in the physiologic circumstances such as embryonic development, placenta formation, and wound healing. It is also crucial to progress of pathogenic processes of a variety of disorders, including tumor growth and metastasis. In general, angiogenesis process is a multi-factorial and highly structured sequence of cellular events comprising migration, proliferation and differentiation of endothelial cells and finally vascular formation, maturation and remodeling. Thereby, angiogenesis inhibition as a helping agent to conventional therapies such as chemotherapy and radiation has attracted the scientists’ attentions studying in this field.

 
Keyword(s): ANGIOGENESIS, TUMOR, METASTASIS
 
References: 
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