Paper Information

Journal:   IRANIAN JOURNAL OF CHEMICAL ENGINEERING   FALL 2010 , Volume 7 , Number 4; Page(s) 42 To 49.
 
Paper: 

MEASUREMENT AND CORRELATION OF IBUPROFEN IN SUPERCRITICAL CARBON DIOXIDE USING STRYJEK AND VERA EOS

 
 
Author(s):  MIRZAJANZADEH M., ZABIHI F.*, ARJMAND M.
 
* ISLAMIC AZAD UNIVERSITY, AYATOLLAH AMOLI BRANCH, DEPARTMENT OF CHEMICAL ENGINEERING, AMOL, IRAN
 
Abstract: 

Ibuprofen solubility in supercritical carbon dioxide was measured using a dynamic apparatus at a pressure between 80 and 140 bars at three different temperatures, 308.15, 313.15 and 318.15 K. The mole fraction of Ibuprofen in fluid phase was in the range of 0.015 × 10-3 - 3.261 × 10-3 at the mentioned operational condition. Modified Mendez-Santiago and Teja equation were used to check the consistency of the experimental data. Results were correlated using the Stryjek and Vera equation of state with the van der Waals 1-parameter (vdW1) and 2-parameters (vdW2) mixing and combining rules. Interaction parameters along with the percentage of the average absolute relative deviation (%AARD) were displayed. Also, the Lydersen group contribution methods were used for predicting the physicochemical and critical properties of the Ibuprofen.

 
Keyword(s): IBUPROFEN SOLUBILITY, SUPERCRITICAL CARBON DIOXIDE, STRYJEK AND VERA EOS, MENDEZ-SANTIAGO AND TEJA EQUATION
 
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