Paper Information

Journal:   IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)   Fall 2002 , Volume 1 , Number 1; Page(s) 15 To 19.
 
Paper: 

AN INVESTIGATION OF DRUG INTERACTIONS IN HOSPITAL PHARMACY PRESCRIPTIONS

 
 
Author(s):  HAJEBI G.*, MORTAZAVI S.A.R.
 
* Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
 
Abstract: 
Drug therapy is a complex and important process and because of the importance of drug interactions, especially in in-patients, accompanying problems and obstacles would exist as a result of concomitant use of drugs in these patients. For this purpose 3130 prescription order forms from Bou-Ali hospital were collected and all potential drug interactions present were extracted and evaluated in terms of significance, severity, documentation and onset.
Interactions were divided into 5 groups based on their significance, with group 1 being the most important and group 5 the least important.
Most interactions observed belonged to groups 4 and 5, accounting for 68.5% of all interactions.Group 1 interactions only accounted for 7.8% of all interactions observed.
When considering the onset of interactions, the most dominant type (55.8% of all interactions) were the slow-occurring ones. In terms of the severity, most interactions (47.2%) were of the medium (moderate) type. Strong (severe) interactions only accounted for 8.2% of all interactions.
Finally, in terms of the documentation of interactions, the most prevalent type were the probable ones, accounting for 56.8% of all interactions observed. Definite interactions only accounted for 4.3% of all interactions.
 
Keyword(s): DRUG INTERACTION; HOSPITAL PRESCRIPTION; PRESCRIPTION; SIGNIFICANCE OF INTERACTION
 
References: 
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