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Paper Information

Journal:   JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES   Winter 2004 , Volume 3 , Number 1; Page(s) 44 To 51.
 
Paper: 

THE PREVALENCE OF HEPATITIS B INFECTION IN PATIENTS SUFFERING FROM LICHEN PLANUS IN KERMAN DURING THE YEAR 1381

 
 
Author(s):  ESFANDIARPOUR I.*, RAHNAMA Z., FAHIMY F., SALARI Z.
 
* Dept. of Dermatology, Kerman University of Medical Sciences, Kerman, Iran
 
Abstract: 

Background: Lichen planus (LP) is an inflammatory papulosquamous which has been found to be associated with liver disease, particularly hepatitis B (HBV) infection in several studies.
Regarding the increasing of the prevalence of hepatitis B in our community, and the importance of the infection caused by this virus, which is among the man health problems; we conducted a descriptive and cross-sectional study in Kerman population for evaluatiof the prevalence of cases with positive hepatitis B virus surface antigen (HBsAg) in patients suffering from LP compared to the general population, that is 1-2%.
Materials and Methods: 120 patients with LP (case group) and 183 healthy volunteer blood donors (control group) were studied during 10 months in 1381 in specialized dermatology clinics of Kerman city.
LP was diagnosed by clinical manifestation, physical examination and skin biopsy. HBsAg was detected in cases and control group by Elisa method.
Results: The mean age of the individuals was 35.75±1.45 for case group and 32.7±0.7 for control group. 57(47.5%) of patients in case group were female and 63 (52.5%) were male. In control group 46 (25%) were female and 137 (75%) were men.
The results showed that the most common site of Lp involvement was upper limb (67.5%) and the most frequent clinical types were mucosal (67.5%) and classical forms (65%) respectively.
One of the patients with Lp (0.8%) and four controls (2.2%) were HBsAg positive. These values were not statistically significant.
Conclusion: Our findings indicated that a search for HBV infection in all patients with lichen planus is not necessary. A large multicentric studies should be conducted in other areas of the country.

 
Keyword(s): HEPATITIS B, LICHEN PLANUS, KERMAN
 
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