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Paper Information

Journal:   IRANIAN INTERNATIONAL JOURNAL OF SCIENCE   Spring 2002 , Volume 3 , Number 1; Page(s) 127 To 127.
 
Paper: 

HOW MANY SUBJECTS? – A BAYESIAN APPROACH TO THE DESIGN OF A CLINICAL TRIAL

 
 
Author(s):  PEZESHK H.*
 
* Tehran, Iran
 
Abstract: 
An inferential Bayesian framework for sample size determination for a clinical trial is presented. It is assumed that the data are from a normal distribution for which the variance is known. We shall apply a Bayesian argument to show how we may use the prior information on the two treatment effects to decide how many patients are needed in each of these two groups
 
Keyword(s): CLINICAL TRIALS; SAMPLE SIZE DETERMINATION; INFERENTIAL BAYESIAN APPROACH; NUMBER OF PATIENTS IN EACH OF THE TWO TREATMENT GROUPS
 
References: 
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