Paper Information

Journal:   HARAKAT   Winter 2001 , Volume - , Number 10; Page(s) 87 To 106.
 
Paper: 

THE EFFECT OF HYPERGLYCEMIA ON CARBOHYDRATE METABOLISM DURING PROLONGED INTENSE EXERCISE

 
 
Author(s):  MOHEBI HAMID*
 
* UNIVERSITY OF GUILAN
 
Abstract: 

In the present study the effects of hyperglycemia (i.e., 12 mmol/l) throughout prolonged intense exercise on carbohydrate metabolism were examined. Eight male subjects undertook two trials during which they exercised on a cycle ergometer at an intensity of -70% V02max for 120 min. In the first trial (trial A), subjects had their blood glucose concentration clamped at 12 mmol/l, 30 min before exercise and throughout exercise, The same rate and volume of infusion of 0.9% saline as had occurred for trial A were used in a placebo trial (trial B).
Calculated of the rates of total carbohydrate oxidation showed that trial A resulted in significantly higher values when compared with trial B (P<0.01), and the maximal rates of glucose infusion varied between 1.33 and 2,78 glmin at 100-120 min. Musccleglycogen concentrations were significantly depleted (P<0.01) after both trials (170 vs. 206,umol/g dry Wt.). This apparent difference between two trials may be accounted for by storage of 22.6g glucose during the 30-min prime infusion.
The results of this study confirm that maintained hyperglycemia promotes carbohydrate oxidation and glucose uptake, and it does not affect sparing muscle glycogne. However hyperglycemia may spare other carbohydrate sources, especially hepatic reservoirs.

 
Keyword(s): GLUCOSE UTILIZATION, CARBOHYDRATE OXIDATION, FAT OXIDATION, MUSCLE GLYCOGEN, GLUCOSE CLAMP TECHNIQUE
 
References: 
  • ندارد
 
  Yearly Visit 36
 
Latest on Blog
Enter SID Blog