Paper Information

Journal:   TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)   2004 , Volume 62 , Number 4; Page(s) 326 To 331.
 
Paper: 

HISTOLOGIC FINDINGS OF UTERINE CERVIX AMONG WOMEN WITH CYTOLOGIC DIAGNOSIS OF ASCUS (ATYPICAL SQUAMOUS CELLS OF UNDERMINED SIGNICANCE)

 
 
Author(s):  GHAEM MAGHAMI FATEMEH, ENSANI F., BEHTASH N., HOSSEINI NEJAD S.E.
 
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Abstract: 

Background: The aim of this investigation is to evaluate the histologic results of biopsy in women with atypical squamous cells of undetermined significance (ASCUS) cytologic diagnosis.
Materials and Methods: We reviewed a series of cases with ASCUS pap smears from March 1999 to Feb 2002 in
Imam Khomeini Hospital (n= 104), Who had cervical biopsy indirected colposcopy (103) and in Onec endocervical biopsy obtained without colposcopy. In 60 patients before colposcopy and biopsy repeat pap smear was tabled.
Results: Biopsy revealed 28.8% SIL (14 LSIL and 16 HSIL),1 invasive carcinoma and 1 endometrial carcinoma. Pap smear repeated for 60 women before colposcopy examination, which 7 (11.7%) of them were normal. ASCUS persisted in 45 cases (75%) and 8 cases (13.3%) turned out to be SIL (6 LSIL, 2 HSIL) of 7 normal repeat smear, 2 marked as LSIL by biopsy. In colposcopic examination 22 of 103 (21.4%) had normal view which one of them was LSIL histologically.
Conclusion: Based on these findings, it seems immediate colposcopy and directed biopsy are appropriate procedures for management of ASCUS and to detect underlying SIL.

 
Keyword(s): COLPOSCOPY, PAP SMEAR, CERVICAL BIOPSY, ASCUS, SIL
 
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