Paper Information

Journal:   TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)   2004 , Volume 62 , Number 3; Page(s) 194 To 203.
 
Paper: 

ANKLEF8RACHIAL INDEX AS A VALID PREDICTIVE TEST FOR DETECTION OF PERIPHERAL ARTERIAL DISEASE, TO FORETELL THE POSSIBILITY OF ISCHEMIC HEART DISEASES IN DIABETIC PATIENTS

 
 
Author(s):  RAFIEI M.*, SADR BAFGHI S.M.H., AFKHAMI ARDEKANI MOHAMMAD, NAMAYANDEH S.M., ORAFA A.M., AHMADIEH M.H.
 
* 
 
Abstract: 

Background: To evaluate the ability of Ankle/Brachial Index (ABI), that is a sensitive and specific test for detection of PAD, to foretell the possibility of ischemic heart diseases in diabetic patients.
Materials and Methods: All of diabetic patients who visited in our diabetes research center between May 2000 and May 2001 and were confirmed diabetics since 2 or more years ago were enrolled in the study. The ABI was calculated for all of the patients and their demographic specifications and ischemic heart disease risk factors were recorded. All of the patients refer to perform an exercise test, but 279 patients were conferred to performing stress test. They were containing: 127 patients with ABI =<1.1(group I) and 47 patients with ABI>=1.4 (group Ill) as case groups and, 105 patients with 1.1<ABI<1.4(group II) as control group underwent an exercise test according to the "Bruce protocol.
Results: 497 patients (52.4%) were women, and 451 patients (47.6%) were men. The mean age was 55.25
± 10.08 years. 57% of participants had high blood pressure with superiority of female (P = 0.002).10.2% of the patients had an ABI= 60 years (P = 0.02). 238 patients were in group I (25.1 %),625 patients in group II (65.9 %) and 85 patients in group III (9 %). 52.8% of 125 patients in Group I, 19.6% of 107 patients in group II, and 44.7% of 47 patients in Group III had positive exercise test. I, II (P @0.00)- II , III (P = 0.05) A total of 108 patients from among the 279 patients had positive exercise test (38%), and most of them were from groups I &III. 72.2% of group I , and 52.5% of group II had high blood pressure (P ==0.00). Both I . hypertensive and normotensive patients with ABI =<1.1 & >=1.4 had positive exercise test significantly more than patients with 1.1<ABI<1.4. & point="<1.1" cutoff with (ABI) Index Brachial Ankle Conclusion: ="0.003respectively)" (P="0.001&P">=1.4 is an independent predictor of coronary artery diseases in diabetic patients especially in those who are hypertensive.

 
Keyword(s): ANKLE/BRACHIAL INDEX, CORONARY ARTERY DISEASE, PERIPHERAL ARTERIAL DISEASE, EXERCISE TEST, DIABETES MELLITUS
 
References: 
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