Paper Information

Journal:   JOURNAL OF MEDICAL COUNCIL OF I.R.I.   FALL 2004 , Volume 22 , Number 3; Page(s) 184 To 188.
 
Paper: 

EVALUATION OF GIARDIA INFECTION AND COMPARISON OF TWO TREATMENT REGIMENS TO ERADICATE GIARDIASIS IN PATIENTS REFERRED TO LABORATORIES IN THE SOUTH OF TEHRAN

 
 
Author(s):  ZANGENEH M., AMINI F.
 
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Abstract: 

Parasitic infections are one of the most common problems world wide specially in developing countries including our country. one of the commonest parasitic diseases is giardia lamblia. The objective was to compare effect of Metrpnidazol and Furazolidon on Giardiasis to evaluate the frequency of giardiasis in south of Tehran.
The study is cross- sectional prospective. Between 23 october 1999 and 22 nd February 2000, a total numder of 650 stool specimens from patients with abdominal discomfort were collected for giardia lamblia in 3 laboratories that were located in the south of Tehran. Stool specimens were taken at 3 different times and stool exam was performed by conventional methods.
Patients were divided to 3 age groups (0-10 years, 10- 20 years, >20 years) and questions regarding sex, age, symptoms, education, economic, water supply were asked. The patients with positive stool exam for giardia labmblia were divided to two groups, one group took metronidazol and another group took furazolidon, and two weeks after completion treatment their stool exams were repeated.
A total number of 74 stool specimens were positsve for giardia lamblia, 36 (48.64%) men, 38 (51.35%) women; 36 (10.71%) in age group 0 - 10 years, 20 (25%) in age group 10- 20 years, and 18 (7.69%) > 20 years. The most common symptom in children was diarrea and in adult abdominal pain. 88.38% of patients were cured by Metronidazol and 94.11% by Furazolidon. There was no significant difference between metronidazol and furazolidon in the cure of giardia lamblia (P> 0.05, P= 0.6).
In this study, women and age group 10 - 20 were infected more, and educationwas importantin age group 0 - 10 years, therefore, education about water supply, hygiene is effective in controlling giardiasis. Furazolidon was as effective as Metronidazol with fewer side effects, therefore, we can use Furazolidon in treatment of giardiasis.

 
Keyword(s): FURAZOLIDON, METRONIDAZOL, GIARDIA LAMBLIA, TREATMENT
 
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