Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JOURNAL OF MEDICAL COUNCIL OF I.R.I.   SUMMER 2004 , Volume 22 , Number 2; Page(s) 104 To 108.
 
Paper: 

ASSESSMENT OF THE DIAGNOSTIC VALUE OF MICRALTEST FOR DETECTION OF MICROALBUMINURIA IN COMPARISON WITH IMMUNOTURBIDOMETRY, IN DIABETIC PATIENTS

 
 
Author(s):  RAJABIANI A., ESTAKHRI R., ALAVI M.
 
* 
 
Abstract: 

In Patients with long standing diabetes mellitus, microalbuminuria (urinary albumin excretion rate of 20-200 mcglmin which is equivalent to 20-200 mgldl) is a valuable predictor of persistent proteinuria and diabetic nephropathy. Early intervention may prevent or reduce the rate of renal complications. The Micral urinary test strip claims to have the ability of measuring low levels of urinary albumin. This study has tried to assess the performance of Micral-test strip in detecting microalbuminuria.
Ninety patients who were high risk for diabetic nephropathy and hypertension were selected. Those who had obvious proteinuria detectable with routine urinary test tapes, were excluded. In selected cases urinary albumin and protein were measured by Micral-test strip, precipitation method, urinary albumin to creatinine level, compared with standard immunonephelometry method. Albumin concentration> 20 mg/L, total 24 hours protein excretion> 150 mg and albumin(mg) / creatinine (gr)> 30 Were considered as cut off points for determination of microalbuminuria and proteinuria. The results show specificity of micral-test, total protein of 24h urine and the ratio of urinary albumin / creatinine ratio as 59%, 75% and 77%, respectively arid the sensitivity of these tests as 93%, 54% and 89%, respectively.
Comparison of this results demonstrate that using 24 hours urinary protein which is used in most laboratories, to detect proteinuria does not have an acceptable sensitivity and specificity. Micral-test strip although having a high sensitivity has a low specificity, but if used along with urinary albumin / creatinine ratio, could yield better results.

 
Keyword(s): MICROALBUMINURIA, MICRAL-TEST, DIABETIC NEPHROPATHY
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 71
 
Latest on Blog
Enter SID Blog