Paper Information

Journal:   JOURNAL OF MEDICAL COUNCIL OF I.R.I.   SUMMER 2004 , Volume 22 , Number 2; Page(s) 75 To 79.
 
Paper: 

EVALUATION OF DIAGNOSTIC VALUE OF FINE NEEDLE ASPIRATION BIOPSY (FNAB) IN PERSISTENT CERVICAL LYMPHADENOPATHY IN DR. SHARIATI HOSPITAL DURING 2000 AND 2001

 
 
Author(s):  SOROUSH A.R., NARI M., TAVANGAR S.M., MAHMOUDZADEH H., KAMALIAN A., HEDAYAT A.
 
* 
 
Abstract: 

Fine needle aspiration biopsy (FNAB) is a safe, simple, and cost -effective method for the evaluation of palpable persistent (>3 wk.) lymphadenopathy. Differential diagnosis of persistent cervical lymphadenopathy is widely variable and include benign disorders & malignancies (primarye.g. Lymphomas & secondary including metastases). In a procedure evaluation study, we evaluated 61 cases of persistent lymphadenopathy referred to the Dr.Shariati s hospital in 2000 - 2001 in whom no cause for the lynphadenopathy could be found. We initially performed FNA and then open biopsy from the same lymph node. The specimens are evaluated for cytology and histopathology respectively by two pathologists in a double blind manner.
Diagnosis was classified into three categories including: benign disorders, lymphomas, and metastatic carcinomas that in the FNAB group included 37.8%, 31.1%, 31.1% respectively and in the open biopsy group included 29.5%, 36.1%, 34.4% of patients respectively. In 55 patients the results of FNAB and open biopsy were similar. Out of the remainder, in 4 patients the result of FNAB was benign and of the open biopsy as lymphoma. In the other 2 patients the result of open biopsy showed metastatic carcinoma and of the FANB showed benign in one and Iymphomainanother. Sensitivity, specificity, positive and negative predictive values, and accuracy of FNAB in contrast to open biopsy for benign disorders are 100%, 88.4%, 78.3%, 100% and 91.8% respectively. The above values for lymphomas are 81.8%, 97.4%, 94.7%, 90.5% and 91.8% and for metastatic carcinoma are 90.5%, 100%, 100%, 95.2% and 96.7% respectively.
In all above three diagnostic groups the results of FNAB in contrast to open biopsy are remarkable and it can replace open biopsy for diagnosis of many cases of persistent cervical lymphadenopathy.

 
Keyword(s): FNAB, OPEN BIOPSY, PERSISTENT CERVICAL LYMPHADENOPATHY, CYTOLOGY, PATHOLOGY
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 55
 
Latest on Blog
Enter SID Blog