Paper Information

Journal:   ARCHIVES OF IRANIAN MEDICINE   July 2001 , Volume 4 , Number 3; Page(s) 127 To 129.
 
Paper: 

BOTULINUM TOXIN A (BTX-A) FOR TREATMENT OF PALMAR HYPERHIDROSIS

 
 
Author(s):  GHANEINEZHAD H., HEYDARI MORTEZA*
 
* DEPARTMENT OF DERMATOLOGY, RAZI HOSPITAL, TEHRAN UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 
Background-Palmar hyperhidrosis is a fairly common disease with an unknown etiology. Some treatment modalities have shown benefits, the most recent of which is the injection of botulinum toxin A (BTX-A). We tried to test the beneficial effects of BTX (Dysport) in Iranian patients. Methods-Fifteen volunteers with severe palmar hyperhidrosis, diagnosed by iodine starch test, were enrolled in the study. Employing a standardized scheme, Dysport was injected intradermally into the palmar aspect of patients’ dominant hands. The distal parts of the non-dominant hands were injected by normal saline as control. Follow-up was performed using iodine starch test. Wilcoxon signed rank test was used for comparison between the cases and controls. Results-Satisfactory response to treatment was achieved in 13 out of 15 patients. Comparing the cases with the controls, Dysport showed a significant beneficial effect (p<0.001). Weakness of handgrip was seen in 13 patients. Conclusion-We suggest using Dysport in the treatment of selected cases of severe palmar hyperhidrosis.
 
Keyword(s): HYPERHIDROSIS • BOTULINUM TOXIN A (DYSPORT)
 
References: 
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