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Paper Information

Journal:   JOURNAL OF CURRENT OPHTHALMOLOGY   2004 , Volume 17 , Number 2; Page(s) 1 To 12.
 
Paper: 

CORNEAL THICKNESS MEASUREMENT BY ORBSCAN II IN TEHRAN: A POPULATION BASED, CROSS-SECTIONAL STUDY

 
 
Author(s):  YAZDANI K., FOTOUHI A., HASHEMI H.*, PARSAFAR H., MEHRAVARAN SH., MOHAMMAD K.
 
* Farabi Hospital, Tehran University of Medical Sciences
 
Abstract: 

Purpose: Assessing the corneal thickness in the central, thinnest and peripheral regions of the cornea in an Iranian population and analyzing possible correlations between them and also with independent variables of age, gender, refraction, and iris color.
Method: This is part of the population based, cross-sectional "Tehran Eye Study" (TES).
Among the TES study population, selected through a stratified random cluster sampling method, 800 (399 right and 401 left) eyes of 410 residents of the first four municipality areas of Tehran, aged 14 years and over, were enrolled to be examined with Orbscan II.Analysis was done through calculating the mean, standard deviation, standard error, and 95% confidence interval of the mean for the thinnest, central, and peripheral corneal thicknesses in each eye separately and grouped according to age, gender, subjective refraction, and iris color while considering the design effect. All estimated values have also been directly standardized for age and gender. Only the results of the right eyes are reported.
Results: The participants' mean age (±SD) was 40.9±t16.9 (range; 14-81) years and 60.9% were female. Mean thickness values (±SD) at the central and thinnest points were 555.6:t39.9 and 550.7±t40.6 microns, respectively. The highest corneal thickness related to the superior region, and the most common location of the thinnest point was the inferotemporal quadrant. The mean distance and thickness differences (±SD) between the thinnest and central points were 0.52±0.31 mm and 4.85±6.2 microns, respectively, and proved to be significantly correlated (r=0.708, P<0.001). Sex and refraction showed no significant correlation with corneal thickness.
Subjects in the <20 years age group had thicker corneas in different regions compared to the >20 years age group (P=0.001 for the central and thinnest points, and P<0.001 for the peripheral region). Those with darker irises had thicker corneas (P value; 0.048 to 0.005 for different corneal regions).
Conclusion: This study has provided valuable information concerning corneal thickness measurements as one of the most important eye indices collected from the population of Tehran. We found that sex and refraction had no significant effect on the corneal thickness while age and iris color did. Results of this study can be an important reference for experts in related fields and can also be used for comparison at an international level.

 
Keyword(s): ORBSCAN, POPULATION BASED, CROSS-SECTIONAL, CORNEAL THICKNESS, PACHYMETRY
 
References: 
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