Paper Information

Journal:   JOURNAL OF CURRENT OPHTHALMOLOGY   2004 , Volume 17 , Number 1; Page(s) 37 To 40.
 
Paper: 

EFFECTS OF ATRACURIUM ADDED TO LOCAL ANESTHETICS ON AKINESIA IN PERIBULBAR BLOCK

 
 
Author(s):  SOLTANI MOHAMMADI S.*, SHAH HOSSEINI A.A.R., ASGHARI R.
 
* TEHRAN UNIVERSITY OF MEDAICAL SCIENCES, SHARIATI HOSPITAL
 
Abstract: 

Purpose: To evaluate the effect of atracurium added to local anesthetics on akinesia in peribulbar block.
Methods: In a double blind randomized clinical trial, 60 patients undergoing cataract surgery were allocated to 2 groups and received either 8ml of lidocain-bupivacain plus 0/5 ml nacl 0/9% (group I) or 8ml of the same mixture plus 0/5ml (5 mg) atracurium (group 11).The level of akinesia was graded by an ophthalmologist unaware of group assignment 5, 10, 15 and 20th minutes after block. Data were analized by Student-T Test and Two Sample T-Test; P<0.05 was considered significant.
Results: Onset of akinesia was shorter in group 11(5.6 min) (P=0.000). 6% of group I (n=6) and 90% of group 11 (n=27) had complete akinesia ten minutes after block. 73% of group I (n=22) and 83% of group 11 (n=25) had complete akinesia 15 minutes after block. None of the eyes in group 11required supplementary block, while 2 patients in groupl received additional injection for inadequate akinesia. Duration of akinesia was not statistically different between two groups (P=0.434).
Conclusion: Atracurium (5 mg) added to lidocain-bupivacainmixture for peribulbar block decreases the onset and increase the quality of akinesia without obvious side effects but has no effect on duration of akinesia.

 
Keyword(s): PERIBULBAR ANESTHESIA, ATRACURIUM, AKINESIA
 
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