Paper Information

Journal:   AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)   Winter 2003 , Volume 9 , Number 4 (SN 26); Page(s) 11 To 17.
 
Paper: 

COMPARISON BETWEEN LIDOCAINE, FENTANYL AND PLACEBO ON HEMODYNAMIC CHANGES AFTER INTRATRACHEAL SUCTION IN ICU PATIENTS

 
 
Author(s):  KHOUSHRAFTAR E.*
 
* Department of Anesthesiology, School of Medicine, Hamadan University of Medical Sciences & Health Services, Hamadan, Iran
 
Abstract: 

Suction of endotracheal tube in ICU can cause hemodynamic changes. We compare the effect of lidocaine, fentanyl and placebo on reducing hemodynamic changes following suction in ICU patient.
Patients were divided into three groups, each containing twenty two patients: A- Lidocaine group receiving 1.5 mg/kg lidocaine intravenously two minutes before suction, B- Fentanyl group receiving 3 g/kg fentanyl two minutes before suction, C- Placebo receiving distilled water. The total volume of the three substances was raised to 5 cc. Injecting the drugs and suctioning in a standard technique, we recorded mean arterial pressure, pulse rate, arterial oxygen saturation three times: immediately, after three and six minute's. The recorded information was analyzed.
Based on the results, the injection of Lidocaine before suctioning prevented the hemodynamic changes and hypoxemia, which happened after endotracheal suction. Fentanyl caused hypotension and bradycardia, rejecting the previous reported research. Suctioning in the placebos resulted in hypotension, bradycardia and hypoxemia.
We can use intravenous lidocaine before endotracheal suction to prevent hemodynamic changes in ICU patients.

 
Keyword(s): FENTANYL, HEMODYNAMIC, INTUBATION, INTRATRACHEAL, LIDOCAINE, PLACEBO
 
References: 
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