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Paper Information

Journal:   RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)   2004 , Volume 9 , Number 2 (38); Page(s) 97 To 100.
 
Paper: 

EFFECTS OF TREATMENT OF URINARY TRACT INFECTIONS ON BLOOD AND URINARY ELECTROLYT'S LEVEL

 
 
Author(s):  MOHKAM M., LANGROUDI M., SHARIFIAN M., VALAEI NASER
 
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Abstract: 

Background: Urinary tract infection is one of the most common diseases in neonate, infant and child and has been considered as an important risk factor for development of renal insufficiency or end stage renal disease. Quick diagnosis of acid-base and electrolyte disturbance in pyelonephritic patients and treatment of them can prevent of mentioned complications. In the Present Study the Urinary electorolyte's levels before and after treatment of urinary tract infection in Mofid children hospital were compared.
Materials and methods: In this Quasi Experimental and prospective study (2002-2003), 84 patients with urinary tract infection have been investigated for changes in their serum and urinary electrolytes. Levels of sodium and Potassium in serum have been evaluated before and after treatment with ceftriaxone (75 mg/weight) and also urine random for Na and K have been measurd. Sign test was used for statistical analysis.
Results: 18.8% of the patients were boys and 81.2% were girls. Sodium level in serum increased to 2.69 mEq/L (1.9%, p<0.001) and potassium level also increased to (mEq/l 8.5% p<0.001) after treatment, Random urine Na decreased to 4.2 mEq/L (23.5%, p<0.01) after treatment of pyelonephritis while. random urine postasum was increased in 52% of the patients (N.S). No differences in electrolyte were found between patients with and without obstructive uropathy.

Conclusion: Hyponatraemia and hypokalaemia occurs in young infants with severe acute pyelonephritis in the absence of obstructive urophathy or vesico-ureteric reflux. The severe inflammation of the kidney, itself, may lead to the electrolyte disturbance by a transient resistance of the distal tubule to aldosterone (pseudohypoaldostronism).

 
Keyword(s): ELECTROLYTE DISTUEBANCES, URINARY TRACT INFECTION, PEDIATRICS
 
References: 
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