Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   HORMOZGAN MEDICAL JOURNAL   Spring 2003 , Volume 7 , Number 1; Page(s) 1 To 5.
 
Paper: 

INTERRELATIONSHIP BETWEEN ANTIPHOSPHOLIPID SYNDROME WITH HELICOBACTER PYLORI AND CYTOMEGALOVIRUS

 
 
Author(s):  HAKIM M., HANDJANI A. M.
 
* 
 
Abstract: 

Introduction: The presence of Thromboembolic complications in arteriovenous vessels in antiphospholipid syndrome promoted us to undertake a study to find the relationship between Helicobacter pylori (H. pylori) and cytomegalovirus and their complications, and also to determine if the involvement mechanisms are similar to those which are involved in coronary artery vessels. This study was performed to find infective and inflamatory factors role in thrombosis of antiphospholipid syndrome. This proof could lead to appropriate preventive as well as therapeutic measures.
Method & Material: In this case-control study, 30 patients (25 females and 5 males) with definite diagnosis of antiphospholipid syndrome were included. This group of patients was compared with a control group consisting of 45 healthy cases and antibody production against H. Pylori and cytomegalovirus was assessed in all cases using the ELISA immunofluorescent method.
Results: In 30 cases with antiphospholipid syndrome whose H. Pylori antibody production was checked, 13 cases showed a positive (43.3%) result where as in the control group, this increase was observed in 66.7% (P<0.045). With respect to cytomegalovirus antibody production, in the case-group, 15 cases were positive (50%) while in the control group this figure was 73.3% (P<0.039).
Conclusion: The results of this study demonstrate that in cases with antiphospholipid syndrome, the level of antibody production to H. Pylori and cytomegalovirus is less than in healthy subjects and there is a negative relationship between these two organisms and the thrombosis observed in this syndrome.

 
Keyword(s): ANTIPHOSPHOLIPID SYNDROME, HELICOBACTER PYLORI, CYTOMEGALOVIRUS
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 70
 
Latest on Blog
Enter SID Blog