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Paper Information

Journal:   RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)   Winter 2003 , Volume 9 , Number 31; Page(s) 5451 To 550.
 
Paper: 

METHADONE: A SAFE EFFECTIVE DRUG IN OPUM ADDICT CORONARY ARTERY BYPASS GRAFT (CABG) CASES

 
 
Author(s):  AGHDAEI N., FARASAT KISH R., MOLA SADEGHI ROKABADI GH.A., HEYDARPOUR AVAZ*
 
* shahid Rajaee Hospital, Vali Asr st., Iran University of Medical Sciences and Health Services, Tehran,Iran
 
Abstract: 

Todays coronary artery bypass graft (CABG) is the most frequent among open heart surgeries. In our country some of people that are candidate for coronary artery bypass graft, are addict and they use opium daily, that cause multiple complication during intraoperative and postoperative periods. Inspite of several studies that methadone is used to anti-addiction therapy and for reducing the complications of opium, we decided to choose methadone as perioperative narcotic. Methadone is a long acting synthetic narcotic that we think it can be a good choice narcotic for coronary artery bypass graft. In a trial study, we choose 120 cases among the coronary artery bypass graft patients. Before induction of anesthesia, all of them received 0.6 mg/kg methadone intravenously and in the postoperative period they received 0.15 mg/kg methadone intravenously. 80.83% of this patients didn’t have pain during intraoperative and postoperative periodsand we didn’t see withdrawal syndrom in intensive care unit. In 7.5% of this cases we had to use oralopium in postoperative period.

 
Keyword(s): METHADONE, CORONARY ARTERY BYPASS GRAFT (CABG), ADDICTION, ANESTHESIA
 
References: 
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