Paper Information

Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   WINTER 2008 , Volume 25 , Number 87; Page(s) 103 To 107.
 
Paper: 

A RARE CASE WITH CONGENITAL ANOMALIES IN UPPER AND LOWER LIMBS

 
 
Author(s):  NOURAEI M.H.*
 
* KASHANI HOSPITAL, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Background: Consumption of teratogenic drugs is one of the causes of congenital limb deficiencies.
Case Report: A one-month old neonate is reported who had neither finger and toes, nor metatarsal and metacarpal bones; this is a rare type of congenital disorders. There was no history of congenital anomaly in relatives, and the parents had a consanguineous marriage.
From two years before pregnancy until the end of the second month of pregnancy, the mother consumed Amitriptyline and Chlordiazepoxide.
Conclusion: Given that the mother consumed drugs during the first two months of pregnancy and considering the lack of family history of congenital anomalies, the reported anomalies in the neonate might be associated with drug use in mother. It is necessary to increase the knowledge of women in reproductive age group about using drugs only with physician prescription.

 
Keyword(s): CONGENITAL ANOMALY, CONGENITAL LIMB DEFICIENCY, DRUG
 
References: 
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