Paper Information

Journal:   JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE   WINTER 2007 , Volume 28 , Number 56; Page(s) 56 To 61.
 
Paper: 

COMPARISON OF THE EFFECTS OF FENTANYL DIAZEPAM AND PROPOFOL-DIAZEPAM ON SEDATION OF PATIENTS IN CATARACT EXTRACTION

 
 
Author(s):  GHAEMI MAHDI, ANSARI MAJID
 
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Abstract: 

Background: Administration of a sedative drug for the patients who undergo ophthalmic procedure with regional anesthesia will decrease anxiety and increase cooperation and tolerance of patients. For this purpose drugs with minimal side effects must be used. The goal of this study is to evaluate the effects of the combination of fentanyl-diazepam on sedation of patients in cataract extraction and its comparison with propofol-diazepam.
Materials and Methods: In this clinical trial study, 100 patients who were the candidates for cataract extraction were divided in two groups. In one group, fentanyl (1.5
mg/kg) with diazepam (0.04mg/kg) was administered. The other group received propofol (40mg/kg/min) and diazepam (0.04mg/kg) Sedation score, BP, PR and SPO2 were recorded during the operation period. Recall score, satisfaction of patients and post operation complications were recorded in the recovery ward. The results were compared between two groups.
Results: The mean sedation score, recall score and satisfaction of patients were (3.1
±0.6), (2.1±0.5) and (2.1±0.7) respectively in fentanyl-diazepam group. In propofol-diazepam group, results were (2.2±9.5), (2.2±0.4) and (2±0.4) respectively. Sedation score was significantly higher in fentanyl-diazepam group than the other one. No major side effects, e.g apnea, patient's movement and postoperative compilications were observed in the two groups.
Conclusion: We conclude that fentanyl-diazepam combination provides reliable degree of sedation and decrease recall with minimal side effects in cataract surgery with regional anesthesia. This combination is
better than propofol-diazepam administration.

 
Keyword(s): CATARACT, SEDATION, RETROBULBAR BLOCK, ANESTHESIA
 
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