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Paper Information

Journal:   TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)   2006 , Volume 63 , Number 12; Page(s) 1025 To 1031.
 
Paper: 

ACUTE BACTERIAL MENINGITIS IN ADULTS AND FACTORS INFLUENCING MORTALITY AND SEQUELAE

 
 
Author(s):  ABDI LIAEI Z., MOHRAZ M., HAJSEYED JAVADI H.
 
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Abstract: 
Background: The present study was undertaken to define prognostic factors in adult acute meningitis patients to improve the therapeutic strategy for this disease.
Material & Methods: Over ten years (1991-2001), 131 patients were identified in a cross sectional study as having bacterial meningitis in three university referral hospitals (Imam, Shariati, Sina ), and prognostic factors evaluated to determine CNS complications and outcomes.
Results: Age and patients mental status on admission and delay in referring to hospitals were important predisposing factors. (p=0.003, p<0.001). The most frequent pathogen in CSF culture was pneumococcus and although gram negative bacterial were rare, but they have fatality rate of 90 percent.
Conclusions: Despite the availability of new antibiotics, bacterial meningitis is associated with a high mortality and squeal rate, so efforts should be directed toward early initiation of appropriate antibiotic therapy, especially in old age groups and patients with initial changes in mental status in this potentially fatal disease.
 
Keyword(s): MENINGITIS, PROGNOSTIC FACTORS, CNS COMPLICATIONS
 
References: 
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