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Paper Information

Journal:   JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY   2006 , Volume - , Number 1 (36); Page(s) 13 To 18.
 
Paper: 

STUDY ON THE RESISTANCE OF HALOFERAX RADIOTOLERANS, AN EXTREME HALOPHILIC ARCHAEBACTERIUM FROM UROMIA LAKE AGAINST ULTRAVIOLET (UV) LIGHT AND 60CO GAMMA-RAYS

 
 
Author(s):  ASGARANI E.*, SHIRZAD M., SOOUDI M.R., SHAH MOHAMMADI HAMID REZA, FALSAFI T.
 
* BIOLOGY DEPT., FACULTY OF SCIENCE, AZZAHRA UNIVERSITY, TEHRAN, IRAN
 
Abstract: 

In this work, the capacity of an extreme halophilic archaebacterium, isolated from Uromia lake, Haloferax radiotolerans to withstand the lethal effects of ultraviolet light (UV), and 60Co r-rays has heen studied. The resistibility of this organism against the DNA-damaging agents was evaluated by calculating of the survival fractions at different dose rates of UV and 60Co r-rays radiations and compared with those of Escherichia coli B/r (a radioresistant strain of E. coli). D37 values for Haloferax radiotolerans and E. coli B/r were 231, and 9 J/m2, respectively, by exposure to the UV light. They were 645, and 99 Gy, respectively, by exposure to 60Co r-rays. Against these agents, Haloferax radiotolerans shows much more resistance compare to that of E. coli B/r. This is catogorized as the first report of resistibility in the member of Archaea.

 
Keyword(s): ARCHAEBACTERIA, HALOFERAX RADIOTOLERANS, IRRADIATION, ULTRAVIOLET LIGHT (UV), GAMMA RAYS, D37 VALUE, DNA DAMAGES
 
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