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Paper Information

Journal:   IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY   FALL-WINTER 2008 , Volume 10 , Number 2; Page(s) 113 To 118.
 
Paper: 

EVALUATION OF THE RELATIONSHIP BETWEEN PITYRIASIS VERSICOLOR AND CONSUMPTION OF ORAL CONTRACEPTIVES

 
 
Author(s):  JAVIDI Z.*, MALEKI MASOUD, FATA A.A.M., NAHIDI Y.
 
* DEPARTMENT OF DERMATOLOGY, IMAM-REZA MEDICAL CENTER, MASHHAD UNIVERSITY OF MEDICAL SCIENCES (MUMS), MASHHAD, IRAN
 
Abstract: 

Introduction: Following national family planning programs in Iran, oral contraceptive pills (OCPs) have been widely used by women in reproductive ages. Although OCPs considered safe in many cases, some complications are rarely reported and its prescription is contraindicated in some disorders. In most references OCP is one of the probable predisposing factors mentioned for pityriasis versicolor Since there are no studies supporting a definite relation between OCP and Pityriasis versicolor, the present study was conducted to confirm this theory.
Methods and Material: A case-control study was carried out, from oct 2004 to oct 2005, on samples of female patients (n=186) referring to Dermatology clinic of Imam Reza Hospital in Mashhad. Of these patients, 62 were pityriasis versicolor case group and 124 were the control group. A questionnaire was used as a profile seeking information. The diagnosis was based on clinical manifestations and direct smear of the lesions and Wood lamp findings. Data were analysed by SPSS and statistical tests.
Results: Most of the patients (46.2%) were 20-29 years old. The majority of patients were housewives, mostly rural population (90.3%). There was no considerable association, between rural or urban localizations and pityriasis versicolor (p=0.59). The most common form of the lesions was hyperpigmented and localized ones in upper trunk. Positive family history was recorded in 41.6% of cases, and 7.3% in controls. Cases, 24.2% consumed OCP, indicating that there was no significant relationship between OCP consumption and pityriasis versicolor (p=1.00). All OCP users used LD (Low Dose) pills.
Conclusion: According to this study OCPs do seem to be a predisposing factor for pityriasis versicolor. OCPs may even have a protective effect on pityriasis versicolor by decreasing the sebum secretion. Therefore a change in contraception method for eradication of Pityriasis versicolor in OCP users is unnecessary.

 
Keyword(s): PITYRIASIS VERSICOLOR, MALASSEZIA, ORAL CONTRACEPTIVE
 
References: 
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