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Paper Information

Journal:   MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI)   JULY 2006 , Volume 20 , Number 2; Page(s) 94 To 97.
 
Paper: 

MINIDOSE BUPIVACAINE – FENTANYL SPINAL ANESTHESIA FOR CESAREAN SECTION IN PREECLAMPTIC PARTURIENTS

 
 
Author(s):  RASOULI S.*, MOSLEMI F., PARISH M., AZAR FARIN R., FATHOLAH ZADEH N.
 
* DEPARTMENT OF ANESTHESIOLOGY, ALZAHRA HOSPITAL, TABRIZ UNIVERSITY OF MEDICAL SCIENCES, TABRIZ, IRAN
 
Abstract: 

Background: Spinal anesthesia for cesarean section is associated with a high incidence of hypotension. The synergism between intrathecal opioids and local anesthetics may make it possible to achieve reliable spinal anesthesia with minimal hypotension using a minidose of local anesthetic.
Methods: Forty-four preeclamptic parturients undergoing cesarean section were randomized in two groups of 22 patients. Group A received a spinal anesthetic of bupivacaine 6 mg plus fentanyl 20
mg, and group B received 12 mg bupivacaine. Hypotension was defined as a 30% decrease in systolic and diastolic pressure from baseline. Hypotension was treated with intravenous ephedrine boluses 2.5-5 mg up to maximum 50 mg.
Results: All patients had satisfactory anesthesia. Five of 22 patients in group A required ephedrine, a single dose of 5 mg. Seventeen of 22 patients in group B required vasopressor support of blood pressure. The lowest recorded systolic, diastolic and mean blood pressures as fractions of the baseline pressures were 71.2%, 64.5% and 70.3% versus 59.9%, 53.5% and 60.2% respectively for group A versus group B.
Conclusion: A “minidose” of 6 mg bupivacaine in combination with 20
mg fentanyl may provide satisfactory spinal anesthesia for cesarean section in the preeclamptic patient. The minidose combination caused dramatically less hypotension than 12 mg bupivacaine and nearly eliminated the need for vasopressor support of blood pressure.

 
Keyword(s): HYPOTENSION, PREECLAMPSIA, SPINAL ANESTHESIA, BUPIVACAINE, FENTANYL
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

RASOULI, S., & MOSLEMI, F., & PARISH, M., & AZAR FARIN, R., & FATHOLAH ZADEH, N. (2006). MINIDOSE BUPIVACAINE – FENTANYL SPINAL ANESTHESIA FOR CESAREAN SECTION IN PREECLAMPTIC PARTURIENTS. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), 20(2), 94-97. https://www.sid.ir/en/journal/ViewPaper.aspx?id=104450



Vancouver: Copy

RASOULI S., MOSLEMI F., PARISH M., AZAR FARIN R., FATHOLAH ZADEH N.. MINIDOSE BUPIVACAINE – FENTANYL SPINAL ANESTHESIA FOR CESAREAN SECTION IN PREECLAMPTIC PARTURIENTS. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI). 2006 [cited 2021August05];20(2):94-97. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=104450



IEEE: Copy

RASOULI, S., MOSLEMI, F., PARISH, M., AZAR FARIN, R., FATHOLAH ZADEH, N., 2006. MINIDOSE BUPIVACAINE – FENTANYL SPINAL ANESTHESIA FOR CESAREAN SECTION IN PREECLAMPTIC PARTURIENTS. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), [online] 20(2), pp.94-97. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=104450.



 
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