Paper Information

Journal:   OLYMPIC   SUMMER 2007 , Volume 15 , Number 2 (SERIAL 38); Page(s) 71 To 80.
 
Paper: 

CORRELATION OF PHYSICAL ACTIVITY WITH SERUM FIBRINOGEN AND HOMOCYSTEINE CONCENTRATION IN ACTIVE, SEDENTARY AND WITH CAD MALES

 
Author(s):  NIKBAKHT H.A., AMIRTASH A.M., GHAROUNI H., ZAFARI A.
 
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Abstract: 

Elevated serum concentration of Homocysteine (Hcy) and Fibrinogen (Fib) have been identified as an Novel Coronary Artery Diseases (CAD) risk factors. Correlated associations between physical activity ratings and established this risk factors have occasionally, but not consistently, been demonstrated. The aim of this Cross-sectional study was to determine and compare of correlated association between physical activity and concentration of serum Fib and Hcy in selected groups of men (40-55 years). This applied and analytical study was designed in three groups of subjects who were voluntarily participated, was based on NHIS and PA-R questionnaire; one as active men [age: 47.86±5.33 (years),BMI:27.96±2.26 (kg/m2), nA= 15] and the second as sedentary men [age:43.53±4.34 (years), BMI: 26.26±2.96 (kg/m2), ns= 15), and the other as men with CAD [age: 48.13±5.85 (years), BMI: 26.44±2.34 (kg/m2), ne = 15]. Estimated VO2 max (Active: 39. 039±2.563, sedentary: 32.647±3.056 and CAD: 30.378±4.275 mL. kg-1.min-1) as an physical activity rating index (independent and/or predictor variable) estimated was based on nonexercise prediction equations for VO2 max was developed by researchers at the university of Houston; using age, physical activity status and body mass index. Dependent and/or criterion variables included fasting serum concentration of Fib (Active: 287.866±51.568, Sedentary: 299.800±49.215 and CAD: 307.200±63.804 mg/dL) and Hcy (Active: 11.733±2.625, Sedentary: 12.400±3.869 and CAD: 11.966±5.111 mmol/L). Serum Hcy and Fib analysis with Enzyme Immunoassay and chronometric methods respectively; using biomerio full automated immunoanalyser. Data analysis with ANOVA (P£0.05) demonstrated that physical activity has not any desirable effect on Hcy (P = 0.898) and Fib (P = 0.630), and Pearson correlation equations association between estimated VO2 max and this variables in two groups is not significant.

 
Keyword(s): CAD, FIB, HEY, PHYSICAL ACTIVITY, VO2 MAX
 
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