Paper Information

Journal:   JOURNAL OF MOVEMENT SCIENCE & SPORTS   WINTER 2006 , Volume 3 , Number 6; Page(s) 125 To 137.
 
Paper: 

GHRELIN AND PHYSICAL ACTIVITY

 
 
Author(s):  GHANBARI NIAKI A., FATHI R.
 
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Abstract: 
Obesity and related disorders are among the leading causes of illness and mortality in the developed countries. To better understand the pathophysiological mechanisms that underlie metabolic disorders, increasing attention has been paid to central regulatory elements in energy homeostasis, including food intake behavior and energy expenditure. Ghrelin, a 28-amino acid peptide with an n-octanoylation indispensable for its biological activity, was originally discovered in rat stomach as the endogenous ligand for the growth hormone secretogogue (GHS) receptor (GHSR).
The secretion of ghreline increases under conditions of negative energy balance, such as starvation, cachexia, and anorexia nervosa. Whereas its expression decreases under conditions of positive energy balance such as feeding, hyperglycemia, and obesity.
 
Keyword(s): GHRELIN, PHYSICAL ACTIVITY, FOOD INTAKE, ENERGY BALANCE
 
References: 
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