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Paper Information

Journal:   JOURNAL OF MEDICINAL PLANTS   SEPTEMBER 2007 , Volume 6 , Number 23; Page(s) 89 To 96.
 
Paper: 

STUDY ON EFFECTS OF TOPICAL USE OF SILYBUM MARIANUM EXTRACT (SILYMARIN) ON U.V. IRRADIATED GUINEA PIG SKIN

 
 
Author(s):  JAMSHIDI AMIR HOSSEIN*, AHMADI ASHTIANI HAMID REZA, NADERI M.M., BOKAEI S., GHOLAM HOSSEINI B.
 
* MINISTRY OF HEALTH AND MEDICAL EDUCATION, FOOD & DRUG LABORATORY RESEARCH CENTER, FDLRC AND INSTITUTE OF MEDICINAL PLANTS, ACECR, TEHRAN, IRAN
 
Abstract: 

Background: Regarding to the skin damages caused by the ultraviolet ray of sun and the need for protective materials against these mal effects, Silymarin was evaluated for the propose.
Objective: In this study, by histopathology studies and surveying the clinical symptoms the external use of an herbaceous (herbal) substance, Silymarin, in protecting the mal effects of ultraviolet ray has been evaluated.
Methods: For the study 60 albino hamsters with same age and gender has been selected and they divided in two groups (each group 30 hamsters) randomly. The hair on the back of all animals shaved in an area about 2 square centimeters. The first group gets 9 miligram Silymarin with 20 micro liter acetone topically, and the second group gets only 20 micro liter acetone topically. Then both groups for 45 days exposed to ultra violet ray, 180milijoule/cm2 each day.
Results and Conclusion: The results of clinical and histopathologic surveys show that topical usage of Silymarin has considerable protective effects against the mal effects of ultra violet ray on skin and this can be a promise for using this herbaceous substance as a topical sun protects substance.

 
Keyword(s): SILYMARIN, SKIN, U.V., CLINICAL FINDING, HISTOPATHOLOGY, GUINEA PIG
 
 
References: 
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Click to Cite.
APA: Copy

JAMSHIDI, A., & AHMADI ASHTIANI, H., & NADERI, M., & BOKAEI, S., & GHOLAM HOSSEINI, B. (2007). STUDY ON EFFECTS OF TOPICAL USE OF SILYBUM MARIANUM EXTRACT (SILYMARIN) ON U.V. IRRADIATED GUINEA PIG SKIN. JOURNAL OF MEDICINAL PLANTS, 6(23), 89-96. https://www.sid.ir/en/journal/ViewPaper.aspx?id=103807



Vancouver: Copy

JAMSHIDI AMIR HOSSEIN, AHMADI ASHTIANI HAMID REZA, NADERI M.M., BOKAEI S., GHOLAM HOSSEINI B.. STUDY ON EFFECTS OF TOPICAL USE OF SILYBUM MARIANUM EXTRACT (SILYMARIN) ON U.V. IRRADIATED GUINEA PIG SKIN. JOURNAL OF MEDICINAL PLANTS. 2007 [cited 2021May11];6(23):89-96. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=103807



IEEE: Copy

JAMSHIDI, A., AHMADI ASHTIANI, H., NADERI, M., BOKAEI, S., GHOLAM HOSSEINI, B., 2007. STUDY ON EFFECTS OF TOPICAL USE OF SILYBUM MARIANUM EXTRACT (SILYMARIN) ON U.V. IRRADIATED GUINEA PIG SKIN. JOURNAL OF MEDICINAL PLANTS, [online] 6(23), pp.89-96. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=103807.



 
 
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