Paper Information

Journal:   IRANIAN JOURNAL OF PEDIATRICS   MARCH 2008 , Volume 18 , Number 1; Page(s) 79 To 82.
 
Paper: 

ENOXAPARIN PLUS TICLOPIDINE: AN EFFECTIVE COMBINATION THERAPY FOR INTRACARDIAC THROMBI IN THALASSEMIA INTERMEDIA

 
 
Author(s):  RAHIMINEZHAD M.S.*, SHARIF KAZEMI M.B., SOTOUDEH K.
 
* HEMATOLOGY DEVISION, CHILDREN’S MEDICAL CENTER, DR. GHARIB AVE., TEHRAN, I.R. IRAN
 
Abstract: 

Objective: Patients with thalassemia intermedia have an increased risk of thrombotic events as compared to the general population.
Case Presentation: We describe two cases of thalassemia intermedia with intracardiac thrombi who failed to response to traditional anticoagulation therapy with Unfractionated Heparin and Aspirin; but thrombolysis occurred following combination therapy with Ticlopidine and Enoxaparin.
Conclusion: Our experience in patients shown combination of Enoxaparin and Ticlopidine is effective for treatment of ventricular thrombus in TI patients.

 
Keyword(s): THALASSEMIA INTERMEDIA, INTRACARDIAC THROMBUS, ENOXAPARIN, TICLOPIDINE
 
References: 
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