Paper Information

Journal:   ACTA MEDICA IRANICA   SEPTEMBER-OCTOBER 2007 , Volume 45 , Number 5; Page(s) 355 To 360.
 
Paper: 

CHILDREN, GASTROESOPHAGEAL REFLUX AND ULTRASOUND

 
 
Author(s):  FALLAHI G., SANEIAN H.*, MAHDIZADEH M., FARAHMAND F.
 
* DEPARTMENT OF PEDIATRIC GASTROENTEROLOGY, SCHOOL OF MEDICINE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

While a few studies have excluded ultrasound as a reliable diagnostic tool in screening for Gastro esophageal reflux disease (GERD) in infant and children, others have referred to ultrasound as the screening test of choice in symptomatic patients and for patients follow-up. In this study, we evaluated the sensitivity and specificity of ultrasound in diagnosing GERD in children. This case- control study involved 56 patients and 50 controls. Inclusion criteria were age below 14 years, exhibiting GERD symptoms, having been chosen as a candidate for esophageal endoscopy and biopsy by a pediatric gastroenterology subspecialist, pathology or 24-hour pH-metry result suggestive of GERD, absence of obstructive gastrointestinal tract diseases, metabolic or other systemic diseases and having received no medications prior to the study. Ultrasound examination was performed for both patients and controls; endoscopy and 24-hour pH-metry were done for all patients and those in control group who had abnormal findings in ultrasound exam. Pediatric gastroenterologist’s final judgment based on clinical and paraclinical findings constituted the gold standard. Sensitivity, specificity, positive predictive value and negative predictive value of ultrasound in diagnosing GERD were 76%, 100%, 100% and 79%, respectively. The mean length of sub diaphragmatic part of esophagus was 6.36 mm shorter in children with reflux than that in subjects without reflux and the difference was significant. Ultrasound can successfully be used as the first diagnostic approach in children with GERD.

 
Keyword(s): ULTRASOUND, GASTROESOPHAGEAL REFLUX, CHILD
 
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