Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   ACTA MEDICA IRANICA   SEPTEMBER-OCTOBER 2007 , Volume 45 , Number 5; Page(s) 339 To 344.
 
Paper: 

PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM

 
 
Author(s):  HASANZADEH GH.R.*, BEHZADI G.
 
* DEPARTMENT OF ANATOMY, SCHOOL OF MEDICINE, MEDICAL SCIENCES, UNIVERSITY OF TEHRAN, TEHRAN, IRAN
 
Abstract: 

The ascending serotonergic projections are derived mainly from mesencephalic raphe nuclei. Topographical projections from mesencephalic raphe nuclei to the striatum were examined in the rat by the retrograde transport technique of HRP (horseradish peroxidase). In 29 rats stereotaxically injection of HRP enzyme were performed in dorsal and ventral parts of striatum separately. The extent of the injection sites and distribution of retrogradely labeled neuronal cell bodies were drawed on representative sections using a projection microscope. Following ipsilateral injection of HRP into the dorsal striatum, numerous labeled neurons were seen in rostral portion of dorsal raphe (DR) nucleus. In the same level the cluster of labeled neurons were hevier through caudal parts of DR. A few neurons were also located in lateral wing of DR. More caudally some labeled neurons were found in lateral, medial line of DR. In median raphe nucleus (MnR) the labeled neurons were scattered only in median portion of this nucleus. The ipsilateral injection of HRP into the ventral region of striatum resulted on labeling of numerous neurons in rostral, caudal and lateral portions of DR. Through the caudal extension of DR on 4th ventricle level, a large number of labeled neurons were distributed along the ventrocaudal parts of DR. In MnR, labeled neurons were observed only in median part of this nucleus. These findings suggest the mesencephalic raphe nuclei projections to caudo-putamen are topographically organized. In addition dorsal and median raphe nuclei have a stronger projection to the ventral striatum.

 
Keyword(s): STRIATUM, DORSAL AND MEDIAN RAPHE NUCLEI, ASCENDING PROJECTION
 
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
  • Not Registered.
 
+ Click to Cite.
APA: Copy

HASANZADEH, G., & BEHZADI, G. (2007). PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM. ACTA MEDICA IRANICA, 45(5), 339-344. https://www.sid.ir/en/journal/ViewPaper.aspx?id=103714



Vancouver: Copy

HASANZADEH GH.R., BEHZADI G.. PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM. ACTA MEDICA IRANICA. 2007 [cited 2021July27];45(5):339-344. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=103714



IEEE: Copy

HASANZADEH, G., BEHZADI, G., 2007. PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM. ACTA MEDICA IRANICA, [online] 45(5), pp.339-344. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=103714.



 
  pdf-File
Yearly Visit 39
 
 
Latest on Blog
Enter SID Blog