Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)   WINTER 2008 , Volume 14 , Number 57; Page(s) 83 To 90.
 
Paper: 

COMPARISON OF EFFECT OF MEPERIDINE AND TRAMADOL TREATMENT ON POSTOPERATIVE SHIVERING IN ELECTIVE CESAREAN SECTION

 
 
Author(s):  SAHM ALDINI M.A.*, KHADEMI S., MAJIDI F.
 
* FAGHIHI HOSPITAL, ZAND STREET, SHIRAZ UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, SHIRAZ, IRAN
 
Abstract: 

Background & Aim: Postop shivering is a common complication that needs attention and treatment. Mepridine is an effective drug in treatment of shivering but it has important side effects such as respiratory depression. It is also contraindicated in some patients. The aim of this survey was to compare effects of mepredine and tramadol in treatment of postop shivering in order to find a good substitution for mepridine.
Patients and Methods: Ninety women undergoing elective cesarean section under general anesthesia, in ASA class I and II, were enrolled in this double-blind clinical trial. They were randomly divided in three equal groups (n=30 in each group); 1st group received mepredine 0.5 mg/kg, 2nd group received tramadol 0.5mg/kg and 3rd group received tramadol 1mg/kg for treatment of shivering. Data of patients during shivering, time interval between injection of drug and cessation of shivering, incidence of respiratory depression, nausea and vomiting were registered and statistical analysis was done by chi-square test.
Results: Shivering ceased in 1st group after 3.9±1.6min, in 2nd group after 4.8±2.6 min and in 3rd group after 2.6±1.1 min (p<0.05). Incidence of respiratory depression in 1st group was %6.66, in 2nd and 3rd groups it was zero (p<0.05). Incidence of nausea and vomiting in 1st group was %13.3, in 2nd group %10 and in 3rd group it was %16.6(P<0.05).
Conclusion: According to these findings, tramadol can be substituted with mepredine in treatment of postop shivering and dose of 1mg/kg of tramadol is suggested.

 
Keyword(s): SHIVERING, TRAMADOL, MEPERIDINE, ELECTIVE CESAREAN SECTION
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 60
 
Latest on Blog
Enter SID Blog