Paper Information

Journal:   MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES   SUMMER 2007 , Volume 50 , Number 96; Page(s) 211 To 216.
 
Paper: 

COMPARISON OF INCIDENCE OF SUCCINYLCHOLINE-INDUCED FASCICULATION AND POSTOPERATIVE MYALGIAS

 
 
Author(s):  TAGHAVI GILANI M., RAZAVI M., NAMI S.R., JAHAN BAKHSH SEYED SAEID
 
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Abstract: 

Introduction: Fasciculation and myalgia are common complications of succinylcholine and decrease of incidence and intensity of them will reduce succinylcholine-induced side effects.

This study was done to evaluate the severity and prevalence of fasciculation and myalgia after succinylcholine and perform a comparison between three groups.

Material and Methods: In this case-control study in 2006, 75 patients with ASA I and orthopedic surgery were evaluated in Imam Reza hospital. The patients divided randomly in to three same groups. In first group thiopental and succinylcholine 1.5 mg/kg was injected, in second group propofol 2 mg/kg and succinlycholine 1.5 mg/kg and in third group thiopental and succinylcholine 3 mg/kg was administered. Fasciculation, intubation quality after 1 min, and myalgia after 24 h were analyzed. Demografic parameters, pain scales and fasciculation data were gathered in a questiONNaIr And analyzed by SPSS, descriptive statistics and frequency distribution tables.

Results: Fasciculation rate was %76 in first group, 80% in second group, and %84 in third groups. Myalgia was %24 in first group, %28 in second group, and %20 in third group. There were no significant differences between group 1&2 and also 1&3 with respect to fasciculation, Intubation, and post-operative myalgia.
Conclusion: We concluded that propofol aggregates muscular relaxation versus thiopental, and low-dose versus high-dose of succinylcholine and chang to phase II block had no differences regarding to these complications.

 
Keyword(s): SUCCINYLCHOLINE, PROPOFOL, THIOPENTAL, FASCICULATION, MYALGIA
 
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