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Paper Information

Journal:   ACTA MEDICA IRANICA   JANUARY-FEBRUARY 2008 , Volume 46 , Number 1; Page(s) 69 To 76.
 
Paper: 

PROGESTERONE/ESTRADIOL RATIO IN THE LATE FOLLICULAR PHASE OF LONG GONADOTROPIN -RELEASING HORMONE AGONIST CYCLES DID NOT DIFFER BETWEEN CONCEIVED AND NOT-CONCEIVED WOMEN

 
 
Author(s):  SAFDARIAN L., SOLTANI MOHAMMADI F., RAHIMI E.*
 
* DEPARTMENT OF ANESTHESIOLOGY, SINA HOSPITAL, SCHOOL OF MEDICINE, MEDICAL SCIENCES, UNIVERSITY OF TEHRAN, TEHRAN, IRAN
 
Abstract: 
There is a challenging debate on the effect of premature luteinization on the clinical outcome of ‘controlled ovarian hyperstimulation’ (COH) using long ‘gonadotropin–releasing hormone agonist’ (GnRHa) cycles. Premature luteinization is defined as late follicular progesterone/estradiol ratio more than 1 on the day of human chorionic gonadotropin (HCG) administration. We carried out a retrospective case–control study on 75 conceived cases versus 75 not–conceived control women, receiving long GnRHa cycles in their first cycle of treatment. Premature luteinization developed in 15% of the case group vs. 22% of the control group. Neither the late follicular progesterone/estradiol (P/E2) ratio was significantly different between the two groups, nor the day 3 follicle stimulating hormone (FSH), serum estradiol level on the HCG day, total amount of human menopausal gonadotropins ampoules, number of follicles, retrieved oocytes and transferred embryos. Endometrial thickness was significantly more in the pregnant women than in the non–pregnant group. Premature luteinization seems not to adversely affect the clinical outcome of COH.
 
Keyword(s): LONG GNRHA CYCLES, CONTROLLED OVARIAN HYPERSTIMULATION, PREMATURE LUTEINIZATION, IVF, ICSI, PROGESTERONE/ESTRADIOL RATIO
 
 
References: 
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Click to Cite.
APA: Copy

SAFDARIAN, L., & SOLTANI MOHAMMADI, F., & RAHIMI, E. (2008). PROGESTERONE/ESTRADIOL RATIO IN THE LATE FOLLICULAR PHASE OF LONG GONADOTROPIN -RELEASING HORMONE AGONIST CYCLES DID NOT DIFFER BETWEEN CONCEIVED AND NOT-CONCEIVED WOMEN. ACTA MEDICA IRANICA, 46(1), 69-76. https://www.sid.ir/en/journal/ViewPaper.aspx?id=103233



Vancouver: Copy

SAFDARIAN L., SOLTANI MOHAMMADI F., RAHIMI E.. PROGESTERONE/ESTRADIOL RATIO IN THE LATE FOLLICULAR PHASE OF LONG GONADOTROPIN -RELEASING HORMONE AGONIST CYCLES DID NOT DIFFER BETWEEN CONCEIVED AND NOT-CONCEIVED WOMEN. ACTA MEDICA IRANICA. 2008 [cited 2021May12];46(1):69-76. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=103233



IEEE: Copy

SAFDARIAN, L., SOLTANI MOHAMMADI, F., RAHIMI, E., 2008. PROGESTERONE/ESTRADIOL RATIO IN THE LATE FOLLICULAR PHASE OF LONG GONADOTROPIN -RELEASING HORMONE AGONIST CYCLES DID NOT DIFFER BETWEEN CONCEIVED AND NOT-CONCEIVED WOMEN. ACTA MEDICA IRANICA, [online] 46(1), pp.69-76. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=103233.



 
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